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Associative learning turns DEET from aversive to appetitive in Aedes aegypti journals.biologists.com

exabrial33 minutes ago

The answer is just to use Picaridin instead of DEET, or perhaps a combination of both. Picaridin is sold as "Off - Clean Feel" or in Sawyer products in the USA.

The exact mechanism is not completely understood, but it's thought that DEET works because it interfere's with mosquitos ability to locate their prey. It is not thought to discourage bites as "they don't like the taste", just by interfering with sensing.

A newer repellent, Picaridin, not only interferes with locating prey, but actively deters mosquitos like pepper spray mace. It's an engineered molecule, derived from a compound called piperine, a substance found in black pepper plants.

Studies show that "Picaridin is as effective as DEET", but my personal experience is it is about twice as effective as DEET.

I spend an enormous amount of my free time outdoors and I can attest that Picaridin is far more effective than DEET for both mosquitos and ticks (we have two main species in the Kansas/Missouri/Arkansas region, others are present but less common).

As a personal data point, I had a friend trip on a hike this spring and fall into a grassy/bushy area. He did not put any repellent on. When we stood up, he was _covered_ in ticks. We got back to the truck and started peeling them off him, probably 15+ plus we flicked off or crushed. Unfortunately, we kept finding more, so we tried spraying Picaridin after the damn things hated that stuff so bad they jumped or fell off instantly.

You do not want to get Picaridin in your eyes or mouth, holy shit, that stuff is like bear mace. Also make sure you're downwind when you're spraying, your friends with appreciate that.

The other advantage of Picaridin is that it does not melt certain plastics. If you have life saving gear made of certain plastics, DEET can melt many times of plastics! (Notably some PVCs, polycarbonates, acrylics, acetates, and elastics).

gobdovan10 hours ago

In plain English, they made mosquitos like repellent.

Y-bar9 hours ago

Tldr: Repelln’t.

zeafoamrun9 hours ago

Could this already be happening out in the wild?

cactusplant73744 hours ago

I use a lot of bug spray and I am still swarmed sometimes.

fooquxan hour ago

As I understand it, DEET just prevents biting as they don't like the taste of it, and they taste with their feet. Thus, it doesn't do much to prevent initial attraction.

Edit: thought I'd include a link to a study about this as it's not well known. https://www.cell.com/current-biology/fulltext/S0960-9822(19)...

exabrialan hour ago

I believe DEET interferes with their ability to locate prey actually.

fooquxan hour ago

There may be multiple ways it works, but we don't fully understand all of them. However, here is one study about the feet to show I'm not spouting AI generated bullshit: https://www.cell.com/current-biology/fulltext/S0960-9822(19)...

OutOfHere8 hours ago

I hope these mosquitoes were not released in the wild.

The simple answer would be to add a natural strongly repellent gentle oil to the DEET spray.

GuB-4241 minutes ago

Maybe an effective answer would be to combine DEET with an insecticide.

Mosquitoes attracted to DEET will die because of the insecticide. Usually, for personal protection, we tend to prefer repellents, as we don't want to get bitten, killing the mosquito after the fact is not very useful. But here, the idea is to put some evolutionary pressure against mosquitoes not repelled by DEET.

There are also repellants other than DEET. Icaridin being the best alternative. It is almost as effective as DEET without many of its drawbacks. Some essential oils too, as you said, but I don't think any of them have the effectiveness of icaridin or DEET.

Foobar85687 hours ago

A couple years back, I spray some DEET on my shoes, 5 seconds later, a tiger mosquito tried to bite me on that spot (and yes on the shoe itself, just insane to see it trying ).

They already loved that shit.

exabrialan hour ago

There are no natural oils that have been proven to stay effective, or are effective as DEET.

Go ahead, hose yourself down with Lemon oil, citronella, oil, or lemon eucalyptus oil. They simply do not work.

cbdevidal7 hours ago

Spray made from lemon eucalyptus works[1]. Not as well as DEET, but it works.

[1] https://www.consumerreports.org/health/insect-repellent/oil-...

cbdevidal3 hours ago

I don’t understand why sharing an objective study with good news would be downvoted, someone please explain?

I’m not saying you have to use it; it’s good news for people who have concerns about other chemicals. It works—less effectively, but it works.

“Repellants containing (..) oil of lemon eucalyptus have also been found to be effective.”[1]

[1] Iowa Department of Health, “Controlling Spread of West Nile Virus“ https://hhs.iowa.gov/health-prevention/providers-professiona...

OutOfHere2 hours ago

I have seen the same behavior on this site. Insightful information gets downvoted to -2, and useless comments that merely "feel good" get upvoted to +8.

I think the theory is that each post identifies with a certain topic, e.g. DEET, which identifies with a cultish subset of users surrounding that topic. There is no broad academic curiosity among the cult's members, and they suppress all competing topics as to them they represent other cults.

alwa3 hours ago

And remove the DEET from it, apparently… at least until it loses its appetitive charge.

Until, of course, they learn to like the replacement oil. At which point, break back out the DEET!

plmpsu5 hours ago

Yeah, I would not be surprised if this learned behavior is passed on epigenetically. This is almost like gain of function research potentially.

AyyEye8 hours ago

At that point just skip the deet.

trhway9 hours ago

that explains. I was always wondering why in Siberia (where i worked for 2 summers back then at university times) coming out from house with freshly applied DEET you're getting covered with mosquitos - i was attributing that to the especial ferociousness of the mosquitos there - yet it sounds like the smell of DEET for them in those towns may have become like a BBQ smell for us :)

HPsquared7 hours ago

A bit like how capsaicin was evolved to prevent things being eaten by mammals, but... Well.. humans came along and developed a taste for it.

"Evolution! Can you give me capsaicin, to deter mammals? I want birds to spread my seeds!"

https://youtu.be/1fW2uTRdUJU

tardedmeme5 hours ago

They got the ultimate seed-spreading, since we farm them.

adynaton4 hours ago

Damn, were you working at Tselinoyarsk?

MiracleRabbit9 hours ago

Freshly marinated in DEET

raverbashing6 hours ago

So maybe the solution is to apply DEET to a bug zapper

neves2 hours ago

It was fun, but not a bad idea. Are there mosquito mousetraps, or mosquitotraps?

hattmallan hour ago

Yes, they are mostly attracted to CO2 I think. So some traps that burn propane to attract them. Others I've seen are basically a screen over a fan with a block of dry ice. They use those to collect for like an hour then weigh the mosquitos and test for diseases in a swamp.

aaron6959 hours ago

[dead]

lazide10 hours ago

[flagged]

danparsonson9 hours ago

It's OK, we still have picaridin

jameslk9 hours ago

Picaridin is the better choice as well. DEET is gross stuff that ruins many materials used for outdoor clothes and gear

lazide9 hours ago

I read the paper - if they can train them to like deet this way, picaridin will be child’s play.

OutOfHere8 hours ago

DEET should ruin things less if you stick to 35-40%. There is practically no benefit in going higher anyway. Those using 100% are asking for damage.

Picaridin gives me worsened tinnitus, so I can't use it unless maybe I slowly try to condition myself to it over a week. DEET doesn't.

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